PDB ID 2G47 CHAIN C
Protein name amyloid protein beta A4
PDB 2G47
The number of similar proteins 134
The number of binding states 16
The number of binding partners 6
Coloring
Unicolor (beige)
The number of binding partners
Group

Downdload
 Format:  
Molecule viewer
#binding
partners
  4
  3
  2
  1
  0
Sequence information
1   DAEFRHDSGY   EVHHQKLVFF   AEDVGSNKGA   IIGLMVGGVV     50
Variants
Residue AA Source dbSNP Clinical
Significance
Disease name
2_ALA VAL ClinVar
chr21:27269931
rs193922916 Pathogenic Alzheimer's disease [MedGen:C0002395,OMIM:104300,SNOMED CT:26929004]
21_ALA GLY ClinVar
chr21:27264170
rs63750671 Pathogenic Alzheimer disease, type 1 [MedGen:C2931257]; Alzheimer's disease [MedGen:C0002395,OMIM:104300,SNOMED CT:26929004]; Cerebral amyloid angiopathy, APP-related [MedGen:C2751536,OMIM:605714]; not provided [MedGen:CN517202]
22_GLU GLN ClinVar
chr21:27264168
rs63750579 Pathogenic Cerebral amyloid angiopathy, APP-related [MedGen:C2751536,OMIM:605714]
22_GLU GLY ClinVar
chr21:27264167
rs63751039 Pathogenic Alzheimer disease, type 1 [MedGen:C2931257]; Alzheimer's disease [MedGen:C0002395,OMIM:104300,SNOMED CT:26929004]; Cerebral amyloid angiopathy, APP-related [MedGen:C2751536,OMIM:605714]; not provided [MedGen:CN517202]
22_GLU LYS ClinVar
chr21:27264168
rs63750579 Pathogenic Cerebral amyloid angiopathy, APP-related [MedGen:C2751536,OMIM:605714]; not provided [MedGen:CN517202]
23_ASP ASN ClinVar
chr21:27264165
rs63749810 Pathogenic Alzheimer's disease [MedGen:C0002395,OMIM:104300,SNOMED CT:26929004]; Cerebral amyloid angiopathy, APP-related [MedGen:C2751536,OMIM:605714]; not provided [MedGen:CN517202]