PDB ID 3BLJ     CHAIN A
Protein name Poly(ADP-ribose) polymerase 15
Uniprot Accession Q460N3
The number of similar proteins 74
The number of binding states 2
The number of binding partners 1

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
3BLJ (CHAIN: A)
1 Monomeric state
2 Q460N3  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  1
  0

Sequence information

1   MHHHHHHSSG   VDLGTENLYF   QSMNLPEHWT   DMNHQLFCMV   QLEPGQSEYN   50
51   TIKDKFTRTC   SSYAIEKIER   IQNAFLWQSY   QVKKRQMDIK   NDHKNNERLL   100
101   FHGTDADSVP   YVNQHGFNRS   CAGKNAVSYG   KGTYFAVDAS   YSAKDTYSKP   150
151   DSNGRKHMYV   VRVLTGVFTK   GRAGLVTPPP   KNPHNPTDLF   DSVTNNTRSP   200
201   KLFVVFFDNQ   AYPEYLITFT   A       250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
467_MET LEU 8.3kJPN
chr3:122350959 		-
- 0.0001 -
478_GLU LYS 8.3kJPN
chr3:122350992 		-
- 0.0001 -
482_SER LEU 8.3kJPN
chr3:122351005 		-
- 0.0001 -
488_LYS ASN 8.3kJPN
chr3:122351024 		-
- 0.0001 -
493_ARG TER 8.3kJPN
chr3:122351037 		rs200031878
- 0.0004 -
499_ALA THR VAR_056658 rs34383355
LB/B - -
499_ALA THR gnomAD
chr3:122351055 		rs34383355
- 0.00475989 -
500_ILE VAL gnomAD
chr3:122351058 		rs141924952
- 0.000424143 -
501_GLU GLY 8.3kJPN
chr3:122351062 		-
- 0.0001 -
524_ILE THR gnomAD
chr3:122353931 		rs200127337
- 0.00170018 -
551_GLY SER 8.3kJPN
chr3:122354011 		rs781325096
- 0.0001 -
572_VAL MET 8.3kJPN
chr3:122354690 		-
- 0.0009 -
580_ASP ASN gnomAD
chr3:122354714 		rs149680974
- 0.00138488 -
594_TYR SER 8.3kJPN
chr3:122354757 		-
- 0.0001 -
595_VAL ILE gnomAD
chr3:122354759 		rs145518557
- 0.000362019 -
595_VAL PHE gnomAD
chr3:122354759 		rs145518557
- 0.00139238 -
595_VAL ILE 8.3kJPN
chr3:122354759 		rs145518557
- 0.0031 -
597_ARG GLN gnomAD
chr3:122354766 		rs140321914
- 0.000147205 -
598_VAL LEU gnomAD
chr3:122354768 		rs149846611
- 0.000202888 -
606_GLY ARG VAR_027863 rs12489170
LB/B - -
606_GLY ARG gnomAD
chr3:122354792 		rs12489170
- 0.187081 -
606_GLY ARG 8.3kJPN
chr3:122354792 		rs12489170
- 0.5274 -
607_ARG PRO gnomAD
chr3:122354796 		rs145474072
- 0.00123335 -
633_ARG GLN gnomAD
chr3:122354874 		rs146577543
- 0.00013928 -
640_VAL ALA gnomAD
chr3:122354895 		rs146493543
- 0.00129789 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.