PDB ID 4BSV     CHAIN A
Protein name HETERODIMERIC FC ANTIBODY AZYMETRIC VARIANT 2
Uniprot Accession P01857
The number of similar proteins 345
The number of binding states 28
The number of binding partners 18

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
4BSV (CHAIN: A)
1 P01857  
2 Monomeric state
3 P01857  
4 P02976  
5 P08195  
6 P04626  
7 P02786  
8 P01857   P12314  
9 P01857   P04488  
10 8A47   A0A8B6IYA1  
11 O75015   P01857  
12 7LUR   P01857  
13 7Q3P   7Q3P  
14 7Q15   P55899  
15 184747   1OQO  
16 P01857   3WKN  
17 5XMH   5XMH  
18 P0DOX5   6KA7  
19 P01857   2IWG  
20 P61769   P55899  
21 P01857   P19909  
22 1ADQ   1ADQ  
23 8A49   Q9APG4   Q9APG4  
24 6S5A   6S5A   6S5A  
25 Q6MZV7   8F8W   8F8W  
26 7Q15   P61769   P55899  
27 P0DOX5   P15692   P15692  
28 P01857   2J6E   2J6E   2J6E  

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Only interaction residues
#binding
partners
  >9
  8
  7
  6
  5
  4
  3
  2
  1
  0

Sequence information

1   GTHTCPPCPA   PELLGGPSVF   LFPPKPKDTL   MISRTPEVTC   VVVDVSHEDP   50
51   EVKFNWYVDG   VEVHNAKTKP   REEQYNSTYR   VVSVLTVLHQ   DWLNGKEYKC   100
101   KVSNKALPAP   IEKTISKAKG   QPREPQVYVY   PPSRDELTKN   QVSLTCLVKG   150
151   FYPSDIAVEW   ESNGQPENNY   KTTPPVLDSD   GSFALVSKLT   VDKSRWQQGN   200
201   VFSCSVMHEA   LHNHYTQKSL   SLSPGK       250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
356_ASP GLU VAR_003887 -
LB/B - -
358_LEU MET VAR_003888 -
LB/B - -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

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