PDB ID 4C9B     CHAIN B
Protein name PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG
Uniprot Accession Q9HCG8
The number of similar proteins 5
The number of binding states 5
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   KKKKDELDPL   LTRTGGAYIP   PAKLRMMQEQ   ITDKNSLAYQ   RMSWEALKKS   50
51   INGLINKVNI   SNISIIIQEL   LQENIVRGRG   LLSRSVLQAQ   SASPIFTHVY   100
101   AALVAIINSK   FPQIGELILK   RLILNFRKGY   RRNDKQLCLT   ASKFVAHLIN   150
151   QNVAHEVLCL   EMLTLLLERP   TDDSVEVAIG   FLKECGLKLT   QVSPRGINAI   200
201   FERLRNILHE   SEIDKRVQYM   IEVMFAVRKD   GFKDHPIILE   GLDLVEEDDQ   250
251   FTHMLPLEDD   YNPEDVLNVF   KMDPNFMENE   EKYKAIKKEI   L   300

Variants

Residue AA Source dbSNP Clinical
Significance
Allele
Frequency
(> 0.0001)
Disease name
129_THR ALA gnomAD
chr2:180846546
rs199652450
- 0.00126875 -
161_ALA THR 8.3kJPN
chr2:180843017
-
- 0.0001 -
166_ILE LEU 8.3kJPN
chr2:180843002
rs377130506
- 0.0003 -
178_ILE VAL 8.3kJPN
chr2:180842966
-
- 0.0001 -
180_ILE SER gnomAD
chr2:180842959
rs201915208
- 0.000220097 -
229_ILE MET 8.3kJPN
chr2:180838424
-
- 0.0001 -
309_PRO THR 8.3kJPN
chr2:180835683
-
- 0.0001 -
318_ARG CYS 8.3kJPN
chr2:180835572
rs768520715
- 0.0001 -
361_GLU GLN gnomAD
chr2:180835443
rs143785942
- 0.00120873 -
376_TYR CYS 8.3kJPN
chr2:180835397
rs370024919
- 0.0002 -
401_ILE THR gnomAD
chr2:180835236
rs1471252587
- 0.000288324 -
406_LEU ILE 8.3kJPN
chr2:180830704
-
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.