PDB ID 4CXI     CHAIN A
Protein name KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
Uniprot Accession Q14145
The number of similar proteins 18
The number of binding states 4
The number of binding partners 4

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
4CXI (CHAIN: A)
1 Monomeric state
2 Q14145  
3 Q13618  
4 Q9UF56   P63208  

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Format:

Molecule viewer


Only interaction residues
#binding
partners
  2
  1
  0

Sequence information

1   GSHMGNRTFS   YTLEDHTKQA   FGIMNELRLS   QQLCDVTLQV   KYQDAPAAQF   50
51   MAHKVVLASS   SPVFKAMFTN   GLREQGMEVV   SIEGIHPKVM   ERLIEFAYTA   100
101   SISMGEKCVL   HVMNGAVMYQ   IDSVVRACAD   FLVQQLD     150

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
73_SER ASN gnomAD
chr19:10610492 		rs774932705
- 0.000107501 -
73_SER THR 8.3kJPN
chr19:10610492 		-
- 0.0002 -
91_ALA THR gnomAD
chr19:10610439 		rs202181679
- 0.0002787 -
155_VAL ILE 8.3kJPN
chr19:10610247 		rs780079329
- 0.0001 -
167_VAL PHE VAR_032102 -
US - A lung adenocarcinoma patient
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

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