PDB ID 5O8K     CHAIN A
Protein name Mitotic spindle assembly checkpoint protein MAD2B
Uniprot Accession Q9D752
The number of similar proteins 30
The number of binding states 9
The number of binding partners 6

Coloring

Unicolor (beige)

The number of binding partners

Group

Binding
state		 Binding partners
5O8K (CHAIN: A)
1 Monomeric state
2 O60673  
3 Q6ZNX1  
4 Q9UBZ9  
5 Q9UI95   Q6ZNX1  
6 Q9UBZ9   O60673  
7 Q9UI95   Q86V20   Q6ZNX1  
8 Q9UI95   Q6ZNX1   Q6ZNX1  
9 Q9UI95   Q6ZNX1   Q6ZNX1  

Downdload

Format:

Molecule viewer


Only interaction residues
#binding
partners
  4
  3
  2
  1
  0

Sequence information

1   MTTLTRQDLN   SAQVVADVLS   EFLEVAVHLI   LYVREVYPVG   IFQKRKKYNV   50
51   PVQMSCHPEL   NQYIQDTLHC   VKPLLEKNDV   EKVVVVILDK   EHRPVEKFVF   100
101   EITQPPLLSI   NSDSLLSHVE   QLLRAFILKI   SKVDKVLDHN   PPGCTFTVLV   150
151   HTREAATRNM   EKIQVIKDFP   WILADEQDVH   MHDPRLIPLK   TMTSDILKMQ   200
201   LYVEERAHKN   S         250

Variants

Residue AA Source dbSNP Clinical
Significance
 Allele
Frequency
(> 0.0001)		 Disease name
8_ASP ASN 8.3kJPN
chr1:11740637 		-
- 0.0001 -
49_ASN SER 8.3kJPN
chr1:11740423 		-
- 0.0001 -
51_PRO GLN 8.3kJPN
chr1:11740417 		-
- 0.0001 -
85_VAL GLU ClinVar
chr1:11736983 		rs1057517674
Pathogenic - Fanconi anemia complementation group V|not provided [MONDO:MONDO:0014985,MedGen:C4310652,OMIM:617243|MedGen:CN517202]
93_ARG HIS gnomAD
chr1:11736959 		rs151024263
- 0.000338225 -
124_ARG GLN 8.3kJPN
chr1:11736159 		rs757723800
- 0.0001 -
182_HIS ARG 8.3kJPN
chr1:11735188 		-
- 0.0001 -
206_ARG CYS 8.3kJPN
chr1:11734852 		rs142776270
- 0.0001 -
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Reference

PiSite: a database of protein interaction sites using multiple binding states in the PDB, Miho Higurashi, Takashi Ishida and Kengo Kinoshita, Nucleic Acids Research 2009 37(Database issue):D360-D364

COPYRIGHTc2008-2019 Miho Higurashi, Takashi Ishida and Kengo Kinoshita. All rights reserved.