| PDB ID | 6BWV
|
CHAIN | E |
|---|---|---|---|
| Protein name | Tumor necrosis factor receptor superfamily member 9 | ||
| Uniprot Accession | Q07011 | ||
| The number of similar proteins | 17 | ||
| The number of binding states | 7 | ||
| The number of binding partners | 4 | ||
Coloring
Unicolor (beige)
The number of binding partners
Group
| Binding state |
Binding partners |
|---|---|
| 6BWV (CHAIN: E) | |
| 1 |
P41273
|
| 2 | Monomeric state |
| 3 |
7D4B
|
| 4 |
7YXU
7YXU
|
| 5 |
P41273
P41273
|
| 6 |
6A3W
6A3W
|
| 7 |
6MHR
6MHR
|
Downdload
Molecule viewer
|
Only interaction residues |
|
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|
Sequence information
|
Variants
| Residue | AA | Source | dbSNP | Clinical Significance |
Allele Frequency (> 0.0001) |
Disease name | |
|---|---|---|---|---|---|---|---|
| 47_PRO | LEU |
gnomAD chr1:7998849 |
rs762508142
|
- | 0.000199119 | - | |
| 56_ALA | THR | VAR_018920 |
rs9657963
|
LB/B | - | - | |
| 56_ALA | THR |
gnomAD chr1:7998823 |
rs9657963
|
- | 0.00373827 | - | |
| 100_SER | ASN |
8.3kJPN chr1:7998300 |
rs772618014
|
- | 0.0004 | - | |
| 104_GLN | TER |
ClinVar chr1:7998289 |
-
|
Pathogenic | - | not provided [MedGen:C3661900] | |
| 108_GLN | GLU |
gnomAD chr1:7998277 |
rs147680622
|
- | 0.000205048 | - | |
| 109_GLY | SER | VAR_088225 |
-
|
US | - | Immunodeficiency 109 with lymphoproliferation (IMD109) [MIM:620282] | |
| 109_GLY | SER |
ClinVar chr1:7998274 |
-
|
Pathogenic | - | Immunodeficiency 109 with lymphoproliferation [MONDO:MONDO:0859526,MedGen:C5830346,OMIM:620282] | |
| 115_LYS | ASN | VAR_018921 |
rs9657965
|
LB/B | - | - | |
| 130_ARG | HIS |
8.3kJPN chr1:7997774 |
rs149951504
|
- | 0.0001 | - | |
| 130_ARG | CYS |
8.3kJPN chr1:7997775 |
-
|
- | 0.0001 | - | |
| 134_ARG | TER |
ClinVar chr1:7997763 |
rs771142611
|
Pathogenic | - | not provided [MedGen:C3661900] | |
| 156_VAL | MET |
8.3kJPN chr1:7995151 |
rs1289916547
|
- | 0.0001 | - |